Synaptophysin anticorps

N° du produit ABIN7882406

Cet anticorps anti-Synaptophysin Monoclonal Souris (Clone 3G12) (ABIN7882406) détecte spécifiquement Synaptophysin dans WB. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour Synaptophysin anticorps (ABIN7882406)

Antigène: Synaptophysin (SYP)

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Synaptophysin est non-conjugé

Application: Western Blotting (WB)

Clone: 3G12

Détail du produit anti-Synaptophysin anticorps

Fonction: Synaptophysin Antibody / SYP

Séquence: MLLLADMDVV NQLVAGGQFR VVKEPL

Purification: Affinity purified

Immunogène: Amino acids MLLLADMDVVNQLVAGGQFRVVKEPL from the human protein were used as the immunogen for the Synaptophysin antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Synaptophysin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Synaptophysin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Synaptophysin

Antigène: Synaptophysin (SYP)

Autre désignation: Synaptophysin

Sujet: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity