Recombinant TRIP10 anticorps
Aperçu rapide pour Recombinant TRIP10 anticorps (ABIN7882478)
Antigène
Voir toutes TRIP10 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- TRIP10 Antibody / CIP4
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Purification
- Affinity chromatography
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Immunogène
- A synthetic peptide from human Cdc42-interacting protein 4 / Thyroid receptor-interacting protein 10 protein was used as the immunogen for the TRIP10 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the TRIP10 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store the TRIP10 antibody at -20oC.
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- TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))
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Autre désignation
- TRIP10
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Sujet
- Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. [UniProt]
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UniProt
- Q15642
Antigène
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