TLR8 anticorps

N° du produit ABIN7882501

L’anticorps anti-TLR8 Polyclonal Lapin est utilisé pour la détection de TLR8 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour TLR8 anticorps (ABIN7882501)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TLR8 anticorps

Fonction: Toll-like receptor 8 Antibody / TLR8

Séquence: RLQEVPQTVG KYVTELDL

Purification: Affinity purified

Immunogène: Amino acids RLQEVPQTVGKYVTELDL from the human protein were used as the immunogen for the Toll-like receptor 8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Toll-like receptor 8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Toll-like receptor 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: Toll-like receptor 8

Sujet: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognizes G-rich oligonucleotides.

UniProt: Q9NR97

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades