Chromogranin A anticorps

N° du produit ABIN7884239

Cet anticorps anti-Chromogranin A Polyclonal Lapin (ABIN7884239) détecte spécifiquement Chromogranin A dans IF et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Chromogranin A anticorps (ABIN7884239)

Antigène: Chromogranin A (CHGA)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chromogranin A est non-conjugé

Application: Immunofluorescence (IF), Western Blotting (WB)

Détail du produit anti-Chromogranin A anticorps

Fonction: Catestatin Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the human Catestatin (CHGA352-372)

Purification: Purified

Immunogène: Catestatin 21AA fragment

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: If reconstituted with deionized water in 25 μL: WB: 1:4000, IF: 1:500. Optimal dilution has to be determined by the user.

Buffer: Lyophilised purified in PBS pH 7.4

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détails sur Chromogranin A

Antigène: Chromogranin A (CHGA)

Autre désignation: Catestatin

Sujet:

Cat7, Cst

Chromogranin-A is a secreted protein known as a ""prohormone"" which is found in endocrine cells and neurons and may be released upon stimulation. It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells. Catestatin is a 21 amino acids fragment (352 to 372) from Chromogranin A. It's a bioactive peptide that can stimulate histamine release from mast cells and it's an inhibitor of catecholamines release. Catestatin has been shown to also have cardiovascular functions and antimicrobial activity.

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling