KISS1R anticorps (3rd Extracellular Loop)

N° du produit ABIN7885102

L’anticorps anti-KISS1R Polyclonal Lapin est utilisé pour la détection de KISS1R dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, IF, FACS et LCI.

Aperçu rapide pour KISS1R anticorps (3rd Extracellular Loop) (ABIN7885102)

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Classe de qualité: Carrier-free

Détail du produit anti-KISS1R anticorps

Épitope: 3rd Extracellular Loop, AA 292-305

Fonction: A Rabbit Polyclonal Antibody to Kisspeptin Receptor

Homologie: mouse - 12,14 amino acid residues identical,Rat - 13

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:500

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7235833)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur KISS1R

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Autre désignation: Kisspeptin receptor

Sujet:

Synonyms: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12

Description: The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

ID gène: 84634

UniProt: Q969F8