STX3 anticorps (Cytosolic, N-Term)

N° du produit ABIN7885559

Cet anticorps anti-STX3 Polyclonal Lapin (ABIN7885559) détecte spécifiquement STX3 dans WB, IF et IC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour STX3 anticorps (Cytosolic, N-Term) (ABIN7885559)

Antigène: STX3 (Syntaxin 3 (STX3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STX3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunochromatography (IC)

Classe de qualité: Carrier-free, KO Validated

Détail du produit anti-STX3 anticorps

Épitope: AA 2-16, Cytosolic, N-Term

Fonction: A Rabbit Polyclonal Antibody to Syntaxin 3

Homologie: Mouse,human - identical

Purification: Affinity purified on immobilized antigen.

Immunogène: KDRLEQLKAKQLTQD(C), corresponding to amino acid residues 2-16 of rat syntaxin 3

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7237343)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur STX3

Antigène: STX3 (Syntaxin 3 (STX3))

Autre désignation: STX3

Sujet:

Synonyms: STX3

Description: Syntaxin 3 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2. SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 3, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 3 functions as a plasma membrane protein t-SNARE that is involved in epithelial cell polarization. Indeed, Syntaxin 3 is specifically localized in the apical membrane of polarized epithelial cells where it likely has a role in the polarized trafficking of newly synthesized proteins3.

ID gène: 81802

UniProt: Q08849

Pathways: Synaptic Vesicle Exocytosis