INPPL1 anticorps (pTyr1135)

N° du produit ABIN745748

L’anticorps Lapin Polyclonal anti-INPPL1 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter INPPL1 dans des échantillons de Humain et Souris.

Aperçu rapide pour INPPL1 anticorps (pTyr1135) (ABIN745748)

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPPL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-INPPL1 anticorps

Épitope: pTyr1135

Réactivité croisée: Humain, Souris

Homologie: Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr1135

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur INPPL1

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Autre désignation: INPPL1

Sujet:

Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN.

Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

ID gène: 3636

Pathways: Platelet-derived growth Factor Receptor Signaling