BRD4 anticorps (C-Term)

N° du produit ABIN7938067

L’anticorps anti-BRD4 Polyclonal Lapin est utilisé pour la détection de BRD4 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour BRD4 anticorps (C-Term) (ABIN7938067)

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRD4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BRD4 anticorps

Épitope: C-Term

Fonction: BRD4 antibody (pAb)

Purification: Protein A Chromatography

Immunogène: This BRD4 antibody was raised against a peptide within the C-terminal region of human BRD4.

Isotype: IgG

Information d'application

Indications d'application: *WB: 0.5 - 2.0 μg/mL dilution *For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

Restrictions: For Research Use only

Stockage

Buffer: Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur BRD4

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Autre désignation: BRD4

Sujet:

Background_Plain: BRD4 (Bromodomain-containing protein 4, aka HUNK1) is a chromatin-associated protein with two bromo domains that binds acetylated histone H3 and H4. BRD4 is homologous to Xenopus MCAP, and like MCAP, BRD4 associates with chromosomes during mitosis, predominantly in the non-centromeric regions. A chromosomal aberration involving BRD4 (producing a BRD4-NUT fusion protein) is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. BRD4 is involved in the expression of extracellular matrix gene expression, and its misregulation may be involved in breast cancer progression.

Aliases: CAP, MCAP, HUNK1, HUNKI

Poids moléculaire: 180 kDa

NCBI Accession: NP_490597

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome