Recombinant HDAC3 anticorps

N° du produit ABIN7938149

L’anticorps anti-HDAC3 Monoclonal Lapin est utilisé pour la détection de HDAC3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant HDAC3 anticorps (ABIN7938149)

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 2N1

Détail du produit anti-HDAC3 anticorps

Fonction: HDAC3 antibody (rAb), 100 μg (Clone 2N1)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the HDAC3 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:50000 dilution IHC: 1:50-1:500 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur HDAC3

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Autre désignation: HDAC3

Sujet:

Background_Plain: Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the (amino groups of lysine's located near the amino termini of core histone proteins. At least 4 classes of HDAC were identified. HDAC3 is a class I HDAC. HDAC3 has histone deacetylase activity and may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. The gene encoding HDAC3 is regarded as a potential tumor suppressor gene.

Aliases: HD3, RPD3, RPD3-2

Poids moléculaire: 49 kDa

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development