Recombinant KAT5 anticorps

N° du produit ABIN7938310

Cet anticorps Lapin Monoclonal détecte spécifiquement KAT5 dans IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant KAT5 anticorps (ABIN7938310)

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KAT5 est non-conjugé

Application: Immunofluorescence (IF)

Clone: 230181D5

Détail du produit anti-KAT5 anticorps

Fonction: KAT5 antibody (rAb), 100 μg (Clone 230181D5)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the KAT5 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: IF: 1:200-1:800 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur KAT5

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Autre désignation: KAT5

Sujet:

Background_Plain: KAT5 (K(Lysine) Acetyltransferase 5) is the atalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Aliases: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1

Poids moléculaire: 60 kDa

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway