KDM2B anticorps

N° du produit ABIN7938319

L’anticorps anti-KDM2B Monoclonal Souris est utilisé pour la détection de KDM2B dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour KDM2B anticorps (ABIN7938319)

Antigène: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KDM2B est non-conjugé

Application: Western Blotting (WB)

Clone: K2K842-13

Détail du produit anti-KDM2B anticorps

Fonction: KDM2B antibody (mAb) (Clone K2K842-13)

Purification: Protein A Chromatography

Immunogène: This KDM2B antibody was raised against a peptide containing human lysine-specific demethylase 2B of isoform a.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5 - 2 μg/mL dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur KDM2B

Antigène: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Autre désignation: KDM2B

Sujet:

Background_Plain: KDM2B (lysine (K)-specific demethylase 2B), also known as FBXL10 (F-box and leucine-rich repeat protein 10) is a histone demethylase that preferentially demethylates trimethylated lysine 4 (K4me3) and dimethylated lysine 36 (K36me2) of histone H3. KDM2B displays weak or no activity for mono- and trimethylated H3K36. KDM2B preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which results in inhibition of cell growth and proliferation. KDM2B may also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Aliases: FBXL10

Poids moléculaire: 100 kDa

NCBI Accession: NP_115979

Pathways: Tube Formation, L'effet Warburg