METTL14 anticorps

N° du produit ABIN7938341

Cet anticorps Lapin Polyclonal détecte spécifiquement METTL14 dans WB et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour METTL14 anticorps (ABIN7938341)

Antigène: METTL14 (Methyltransferase Like 14 (METTL14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METTL14 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-METTL14 anticorps

Fonction: METTL14 antibody (pAb)

Purification: Affinity Purified

Immunogène: This antibody was raised against a human peptide containing methyltransferase 14.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000 dilution IP: 4 µL per IP

Restrictions: For Research Use only

Stockage

Buffer: Purified in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur METTL14

Antigène: METTL14 (Methyltransferase Like 14 (METTL14))

Autre désignation: METTL14

Sujet:

Background_Plain: N6-methylated adenine (m6A) is prevalently present in nearly all RNA types and can be found in all organisms from bacteria to humans. It preferentially appears around stop codons and within long internal exons in mammalian messager RNAs. m6A plays an important role in the efficiency of mRNA splicing, processing, translation efficiency, editing and mRNA stability. m6A also takes place in other RNA molecules, such as primary miRNA (pri-miRNAs). METTL14 (methyltransferase-like 14)forms a stable N6-methyltransferase heterodimer complex with METTL3, which catalyzes the generation of m6A modification on mammalian nuclear RNAs. METTL3 is the catalytically active subunit, while METTL14 plays a structural role critical for substrate recognition.

Aliases: Methyltransferase Like 14, EC 2.1.1.62, N6-methyltransferase

Poids moléculaire: 55kDa

NCBI Accession: NP_066012