Recombinant MSH3 anticorps

N° du produit ABIN7938356

L’anticorps anti-MSH3 Monoclonal Lapin est utilisé pour la détection de MSH3 dans des échantillons de Humain et Rat. Il a été validé pour WB.

Aperçu rapide pour Recombinant MSH3 anticorps (ABIN7938356)

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MSH3 est non-conjugé

Application: Western Blotting (WB)

Clone: 1J23

Détail du produit anti-MSH3 anticorps

Fonction: MSH3 antibody (rAb), 100 μg (Clone 1J23)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the MSH3 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:10000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur MSH3

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Autre désignation: MSH3

Sujet:

Background_Plain: MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.

Aliases: MutS Homolog 3, FAP4

Poids moléculaire: 127 kDa

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response