NSUN2 anticorps

N° du produit ABIN7938380

Cet anticorps Lapin Polyclonal détecte spécifiquement NSUN2 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NSUN2 anticorps (ABIN7938380)

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSUN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NSUN2 anticorps

Fonction: NSUN2 antibody (pAb)

Purification: Protein A Chromatography

Immunogène: Peptide within the human NSUN2 (RNA cytosine C(5)-methyltransferase NSUN2) isoform 1.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5 - 2.0 μg/mL dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur NSUN2

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Autre désignation: NSUN2

Sujet:

Background_Plain: NSUN2 (NOP2/Sun Domain Family, Member 2), also called TRM4 (TRNA Methyltransferase 4 Homolog), is a member of NSUN family. It's a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 also methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron containing. tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation.NSUN2 is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Aliases: NOP2/Sun RNA Methyltransferase Family Member 2, Myc-Induced SUN-Domain-Containing Protein, MISU, SAKI, MRT5

Poids moléculaire: 100 kDa

NCBI Accession: NP_060225