Recombinant SIRT3 anticorps

N° du produit ABIN7938489

Cet anticorps anti-SIRT3 Monoclonal Lapin (Clone 2P6) (ABIN7938489) détecte spécifiquement SIRT3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant SIRT3 anticorps (ABIN7938489)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB)

Clone: 2P6

Détail du produit anti-SIRT3 anticorps

Fonction: SIRT3 antibody (rAb), 100 μl (Clone 2P6)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the SIRT3 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:150000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3

Sujet:

Background_Plain: Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive, and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death. full-length hSIRT3 (44 kDa) is an inert protein and that it is activated inside the mitochondria following deletion of 142 amino acids of the N-terminal segment. This processed form of SIRT3 is approximately 28 kDa and possesses deacetylase activity. The full SIRT3 is a 44 kDa protein and is processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product.

Aliases: SIRT-3, Sirtuin 3, Sir1-Like 3, EC 3.5.1

Poids moléculaire: 44 kDa