Recombinant SMAD1 anticorps (pSer214)

N° du produit ABIN7938496

Cet anticorps Lapin Monoclonal détecte spécifiquement SMAD1 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant SMAD1 anticorps (pSer214) (ABIN7938496)

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD1 est non-conjugé

Application: Western Blotting (WB)

Clone: 3K8

Détail du produit anti-SMAD1 anticorps

Épitope: pSer214

Fonction: SMAD1 phospho Ser214 (rAb), 100 μl (Clone 3K8)

Purification: Protein A Chromatography

Immunogène: This information is proprietary to Active Motif and/or its suppliers.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:2000-1:168000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur SMAD1

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Autre désignation: SMAD1

Sujet: SMAD family member 1 (SMAD1) have been involved in metastatic progression of many cancer types. SMAD1) can be induced by many tumor-stimulating cytokines such as the bone morphogenetic protein 2 (BMP2) and TNFa and plays important roles in cell invasion and metastasis. BMP2 signaling is initiated by binding to its specific receptors, which leads to in the phosphorylation and nuclear translocation of Smad1. Translocated SMAD1) then modulates the expression of downstream osteogenic genes.

Poids moléculaire: 52 kDa

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development