Recombinant TARDBP anticorps (pSer409, pSer410)

N° du produit ABIN7938522

Cet anticorps anti-TARDBP Monoclonal Lapin (Clone 6M10) (ABIN7938522) détecte spécifiquement TARDBP dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant TARDBP anticorps (pSer409, pSer410) (ABIN7938522)

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TARDBP est non-conjugé

Application: Western Blotting (WB)

Clone: 6M10

Détail du produit anti-TARDBP anticorps

Épitope: pSer409, pSer410

Fonction: TDP43 phospho Ser409/410 antibody (rAb), 100 μg (Clone 6M10)

Purification: Protein A Chromatography

Immunogène: This information is proprietary to Active Motif and/or its suppliers.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur TARDBP

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Autre désignation: TDP43

Sujet: TDP-43) was first isolated as a transcriptional inactivator binding to the TAR DNA element of the HIV-1 virus. Neumann et al. (2006) found that a hyperphosphorylated, ubiquitinated, and cleaved form of TARDBP, known as pathologic TDP-43, is the major component of the tau-negative and ubiquitin-positive inclusions that characterize amyotrophic lateral sclerosis (ALS) and the most common pathological subtype of frontotemporal lobar degeneration (FTLD-U).

Poids moléculaire: 43 kDa

NCBI Accession: NM_007375

Pathways: Positive Regulation of Peptide Hormone Secretion