XRN1 anticorps (AA 523-1198) (FITC)

N° du produit ABIN7965137

L’anticorps anti-XRN1 Polyclonal Lapin est utilisé pour la détection de XRN1 dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour XRN1 anticorps (AA 523-1198) (FITC) (ABIN7965137)

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRN1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-XRN1 anticorps (FITC)

Épitope: AA 523-1198

Fonction: Anti-XRN1 Antibody FITC Conjugated

Homologie: Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human XRN1 recombinant protein (Position: K523-H1198). Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur XRN1

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Autre désignation: XRN1

Sujet:

Background: 5'-3' exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts ly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

Gene Full Name: 5'-3' exoribonuclease 1

ID gène: 54464

UniProt: Q8IZH2