ADAM15 anticorps (AA 41-456) (Biotin)

N° du produit ABIN7966254

Cet anticorps anti-ADAM15 Polyclonal Lapin conjugué à Biotin (ABIN7966254) détecte spécifiquement ADAM15 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ADAM15 anticorps (AA 41-456) (Biotin) (ABIN7966254)

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM15 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ADAM15 anticorps (Biotin)

Épitope: AA 41-456

Fonction: Anti-ADAM15 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ADAM15 recombinant protein (Position: R41-R456).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ADAM15

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Autre désignation: ADAM15

Sujet:

Background: Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene. This gene is mapped to 1q21.3. The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene Full Name: ADAM metallopeptidase domain 15

ID gène: 8751

UniProt: Q13444