ASXL1 anticorps (AA 14-1541) (Fluoro594)

N° du produit ABIN7966577

L’anticorps anti-ASXL1 Polyclonal Lapin est utilisé pour la détection de ASXL1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ASXL1 anticorps (AA 14-1541) (Fluoro594) (ABIN7966577)

Antigène: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASXL1 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-ASXL1 anticorps (Fluoro594)

Épitope: AA 14-1541

Fonction: Anti-ASXL1 Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ASXL1 recombinant protein (Position: A14-R1541).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ASXL1

Antigène: ASXL1 (Additional Sex Combs Like 1 (ASXL1))

Autre désignation: ASXL1

Sujet:

Background: Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

Gene Full Name: ASXL transcriptional regulator 1

ID gène: 171023

UniProt: Q8IXJ9

Pathways: Retinoic Acid Receptor Signaling Pathway