AMD1 anticorps (Middle Region) (Fluoro488)

N° du produit ABIN7966773

Cet anticorps anti-AMD1 Polyclonal Lapin conjugué à Fluoro488 (ABIN7966773) détecte spécifiquement AMD1 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AMD1 anticorps (Middle Region) (Fluoro488) (ABIN7966773)

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMD1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-AMD1 anticorps (Fluoro488)

Épitope: Middle Region

Fonction: Anti-AMD1 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human AMD1, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur AMD1

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Autre désignation: AMD1

Sujet:

Background: S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC) or AMD1, is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.

Gene Full Name: adenosylmethionine decarboxylase 1

ID gène: 262

UniProt: P17707

Pathways: Ribonucleoside Biosynthetic Process