AMD1 anticorps (Middle Region) (HRP)

N° du produit ABIN7966777

Cet anticorps Lapin Polyclonal détecte spécifiquement AMD1 dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AMD1 anticorps (Middle Region) (HRP) (ABIN7966777)

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMD1 est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AMD1 anticorps (HRP)

Épitope: Middle Region

Fonction: Anti-AMD1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human AMD1, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AMD1

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Autre désignation: AMD1

Sujet:

Background: S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC) or AMD1, is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.

Gene Full Name: adenosylmethionine decarboxylase 1

ID gène: 262

UniProt: P17707

Pathways: Ribonucleoside Biosynthetic Process