ADRBK2 anticorps (C-Term) (PE)

N° du produit ABIN7967054

L’anticorps anti-ADRBK2 Polyclonal Lapin est utilisé pour la détection de ADRBK2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ADRBK2 anticorps (C-Term) (PE) (ABIN7967054)

Antigène: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRBK2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-ADRBK2 anticorps (PE)

Épitope: C-Term

Fonction: Anti-GRK3/ADRBK2 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GRK3, different from the related mouse and rat sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ADRBK2

Antigène: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Autre désignation: ADRBK2

Sujet:

Background: Beta-adrenergic receptor kinase 2  (beta-ARK-2), also known as G-protein-coupled receptor kinase 3  (GRK3), is an enzyme that in humans is encoded by the ADRBK2 gene. The human ADRBK2 gene is located on 22q11. The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Gene Full Name: G protein-coupled receptor kinase 3

ID gène: 157

UniProt: P35626

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling