Amphiregulin anticorps (AA 101-180) (Cy3)

N° du produit ABIN7968147

Cet anticorps anti-Amphiregulin Polyclonal Lapin conjugué à Cy3 (ABIN7968147) détecte spécifiquement Amphiregulin dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Amphiregulin anticorps (AA 101-180) (Cy3) (ABIN7968147)

Antigène: Amphiregulin (AREG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-Amphiregulin anticorps (Cy3)

Épitope: AA 101-180

Fonction: Anti-Amphiregulin/AREG Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Amphiregulin/AREG recombinant protein (Position: S101-R180).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: AREG

Sujet:

Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

Gene Full Name: amphiregulin

ID gène: 374

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway