Ancient Ubiquitous Protein 1 anticorps (AA 77-399) (Fluoro550)

N° du produit ABIN7968391

Cet anticorps Lapin Polyclonal détecte spécifiquement Ancient Ubiquitous Protein 1 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ancient Ubiquitous Protein 1 anticorps (AA 77-399) (Fluoro550) (ABIN7968391)

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ancient Ubiquitous Protein 1 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Ancient Ubiquitous Protein 1 anticorps (Fluoro550)

Épitope: AA 77-399

Fonction: Anti-AUP1 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human AUP1 recombinant protein (Position: A77-R399).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Ancient Ubiquitous Protein 1

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Autre désignation: AUP1

Sujet:

Background: Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene. The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Gene Full Name: AUP1 lipid droplet regulating VLDL assembly factor

ID gène: 550

UniProt: Q9Y679