AGR2 anticorps (AA 21-175) (Biotin)

N° du produit ABIN7969081

L’anticorps anti-AGR2 Polyclonal Lapin est utilisé pour la détection de AGR2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour AGR2 anticorps (AA 21-175) (Biotin) (ABIN7969081)

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGR2 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-AGR2 anticorps (Biotin)

Épitope: AA 21-175

Fonction: Anti-Anterior Gradient 2/AGR2 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Anterior Gradient 2 shares 93.5% amino acid (aa) sequence identity with mouse Anterior Gradient 2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Anterior Gradient 2 recombinant protein (Position: R21-L175). Human Anterior Gradient 2 shares 93.5% amino acid (aa) sequence identity with mouse Anterior Gradient 2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2

Sujet:

Background: Anterior gradient protein 2 homolog (AGR-2), also known as secreted cement gland protein XAG-2 homolog, is a protein that in humans is encoded by the AGR2 gene. Anterior gradient homolog 2 was originally discovered in Xenopus laevis. In Xenopus AGR2 plays a role in cement gland differentiation, but in human cancer cell lines high levels of AGR2 correlate with downregulation of the p53 response, cell migration, and cell transformation. However, there have been other observations that AGR2 can repress growth and proliferation.

Gene Full Name: anterior gradient 2, protein disulphide isomerase family member

ID gène: 10551

UniProt: O95994