APC2 anticorps (N-Term) (HRP)

N° du produit ABIN7969230

Cet anticorps Lapin Polyclonal détecte spécifiquement APC2 dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour APC2 anticorps (N-Term) (HRP) (ABIN7969230)

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC2 est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-APC2 anticorps (HRP)

Épitope: N-Term

Fonction: Anti-APC2 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur APC2

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Autre désignation: APC2

Sujet:

Background: APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

Gene Full Name: APC regulator of Wnt signaling pathway 2

ID gène: 10297

UniProt: O95996

Pathways: Signalisation WNT