APOE anticorps (AA 55-294) (Fluoro647)

N° du produit ABIN7969453

L’anticorps anti-APOE Polyclonal Lapin est utilisé pour la détection de APOE dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour APOE anticorps (AA 55-294) (Fluoro647) (ABIN7969453)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-APOE anticorps (Fluoro647)

Épitope: AA 55-294

Fonction: Anti-Apolipoprotein E/APOE Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse Apolipoprotein E shares 75%,94.6% amino acid (aa) sequence identity with human,rat Apolipoprotein E,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: Apoe

Sujet:

Background: APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

Gene Full Name: apolipoprotein E

ID gène: 11816

UniProt: P08226

Pathways: Regulation of Cell Size, Lipid Metabolism