ARID1A anticorps (Middle Region) (Fluoro594)

N° du produit ABIN7970440

L’anticorps anti-ARID1A Polyclonal Lapin est utilisé pour la détection de ARID1A dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour ARID1A anticorps (Middle Region) (Fluoro594) (ABIN7970440)

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARID1A est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-ARID1A anticorps (Fluoro594)

Épitope: Middle Region

Fonction: Anti-ARID1A Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human ARID1A, identical to the related mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ARID1A

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Autre désignation: ARID1A

Sujet:

Background: AT-rich interactive domain-containing protein 1A, also known as p270, is a protein that in humans is encoded by the ARID1A gene. This gene encodes a member of the SWI/SNF families, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is mapped to 1p36.11. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.

Gene Full Name: AT-rich interaction domain 1A

ID gène: 8289

UniProt: O14497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation