BIK anticorps (AA 1-123) (FITC)

N° du produit ABIN7972414

L’anticorps anti-BIK Polyclonal Lapin est utilisé pour la détection de BIK dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour BIK anticorps (AA 1-123) (FITC) (ABIN7972414)

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIK est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-BIK anticorps (FITC)

Épitope: AA 1-123

Fonction: Anti-Bik Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Bik recombinant protein (Position: M1-R123). Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BIK

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Autre désignation: BIK

Sujet:

Background: Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Gene Full Name: BCL2 interacting killer

ID gène: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity