BMP2 anticorps (C-Term) (Fluoro594)

N° du produit ABIN7972854

Cet anticorps Lapin Polyclonal détecte spécifiquement BMP2 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour BMP2 anticorps (C-Term) (Fluoro594) (ABIN7972854)

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP2 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-BMP2 anticorps (Fluoro594)

Épitope: C-Term

Fonction: Anti-BMP2 Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-2, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BMP2

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: BMP2

Sujet:

Background: BMP2 is also known as Bone morphogenetic protein 2 or BMP2A. It is mapped to 20p12. The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily.?BMP-2, like other?bone morphogenetic proteins,?plays an important role in the development of bone and cartilage. It is involved in the?hedgehog pathway,?TGF beta signaling pathway, and in?cytokine-cytokine receptor interaction. Also, it is involved in cardiac cell differentiation and?epithelial to mesenchymal transition. In addition, BMP2A has been suggested as a reasonable candidate for the human condition fibrodysplasia (myositis) ossificans progressiva, on the basis of observations in a Drosophila model.

Gene Full Name: bone morphogenetic protein 2

ID gène: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation