BCCIP anticorps (AA 167-300) (Fluoro488)

N° du produit ABIN7973171

Cet anticorps anti-BCCIP Polyclonal Lapin conjugué à Fluoro488 (ABIN7973171) détecte spécifiquement BCCIP dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCCIP anticorps (AA 167-300) (Fluoro488) (ABIN7973171)

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCCIP est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-BCCIP anticorps (Fluoro488)

Épitope: AA 167-300

Fonction: Anti-BCCIP Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human BCCIP recombinant protein (Position: K167-K300).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BCCIP

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Autre désignation: BCCIP

Sujet:

Background: BRCA2 and CDKN1A-interacting protein is a protein that in humans is encoded by the BCCIP gene. This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: BRCA2 and CDKN1A interacting protein

ID gène: 56647

UniProt: Q9P287