BUB3 anticorps (AA 50-209)

N° du produit ABIN7973487

Cet anticorps Lapin Polyclonal détecte spécifiquement BUB3 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour BUB3 anticorps (AA 50-209) (ABIN7973487)

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-BUB3 anticorps

Épitope: AA 50-209

Fonction: Anti-BUB3 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-BUB3 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human BUB3 recombinant protein (Position: R50-D209).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BUB3

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Autre désignation: BUB3

Sujet:

Background: BUB3(BUDDING UNINHIBITED BY BENZIMIDAZOLES 3) is a protein that in humans is encoded by the BUB3 gene. And it is mapped on 10q26.13. Bub3 is also a protein involved with the regulation of the Spindle Assembly Checkpoint(SAC), though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the irreversible onset of anaphase through ion of kinetochore localization during prometaphase to achieve biorentation. Bub3 s the localization of Bub1 at the kinetochore in order to activate the SAC. Bub3 also acts as a regulator in that it affects binding of Mad3 to Mad2. Using deletion analysis, the authors identified a domain of BUB1 that is required both for binding BUB3 and for kinetochore localization of BUB1.

Gene Full Name: BUB3 mitotic checkpoint protein

Poids moléculaire: 40 kDa

ID gène: 9184

UniProt: O43684

Pathways: Maintenance of Protein Location