Cadherin 4 anticorps (AA 458-641) (Cy3)

N° du produit ABIN7973874

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 4 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cadherin 4 anticorps (AA 458-641) (Cy3) (ABIN7973874)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-Cadherin 4 anticorps (Cy3)

Épitope: AA 458-641

Fonction: Anti-R-Cadherin-4 CDH4-Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human R Cadherin/CDH4 recombinant protein (Position: K458-D641).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4

Sujet:

Background: Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. It is mapped to 20q13.33. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: cadherin 4

ID gène: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size