IL5RA anticorps (AA 11-110) (Biotin)

N° du produit ABIN747835

Cet anticorps Lapin Polyclonal détecte spécifiquement IL5RA dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IL5RA anticorps (AA 11-110) (Biotin) (ABIN747835)

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-IL5RA anticorps (Biotin)

Épitope: AA 11-110

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-5R alpha

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA/CD125

Sujet:

Synonyms: Interleukin-5 receptor alpha, CD125 antigen, CDw125, HSIL5R3, IL5R, IL-5R, Interleukin 5 Receptor alpha, Interleukin 5 receptor subunit alpha, interleukin 5 receptor type 3, MGC26560, IL5RA, IL-5R alpha, IL5RA_HUMAN.

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

ID gène: 3568

UniProt: Q01344

Pathways: Signalistation JAK/STAT