Cathepsin D anticorps (AA 201-412) (Fluoro488)

N° du produit ABIN7975835

Cet anticorps anti-Cathepsin D Polyclonal Lapin conjugué à Fluoro488 (ABIN7975835) détecte spécifiquement Cathepsin D dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cathepsin D anticorps (AA 201-412) (Fluoro488) (ABIN7975835)

Antigène: Cathepsin D (CTSD)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-Cathepsin D anticorps (Fluoro488)

Épitope: AA 201-412

Fonction: Anti-Cathepsin D/CTSD Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human Cathepsin D shares 84.4%,84% amino acid (aa) sequence identity with mouse,rat Cathepsin D,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human < a href=https://www.bosterbio.com/anti-cathepsin-d-picoband-trade-antibody-a01361-boster.html>Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CTSD

Sujet:

Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

Gene Full Name: cathepsin D

ID gène: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism