Cathepsin D anticorps (AA 161-358) (Biotin)

N° du produit ABIN7975844

Cet anticorps anti-Cathepsin D Polyclonal Lapin conjugué à Biotin (ABIN7975844) détecte spécifiquement Cathepsin D dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Cathepsin D anticorps (AA 161-358) (Biotin) (ABIN7975844)

Antigène: Cathepsin D (CTSD)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Cathepsin D anticorps (Biotin)

Épitope: AA 161-358

Fonction: Anti-Cathepsin D/Ctsd Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse Cathepsin D recombinant protein (Position: K161-Q358).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: Ctsd

Sujet:

Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in signal peptide and a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation of proteins, cell invasion, and apoptosis, playing a significant role in cell signaling technology. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer's disease and it has been considered as a breast cancer tumor marker.

Gene Full Name: cathepsin D

ID gène: 13033

UniProt: P18242

Pathways: Peptide Hormone Metabolism