Cathepsin D anticorps (AA 65-410) (Cy3)

N° du produit ABIN7975867

L’anticorps anti-Cathepsin D Polyclonal Lapin est utilisé pour la détection de Cathepsin D dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Cathepsin D anticorps (AA 65-410) (Cy3) (ABIN7975867)

Antigène: Cathepsin D (CTSD)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-Cathepsin D anticorps (Cy3)

Épitope: AA 65-410

Fonction: Anti-Cathepsin D/CTSD Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse Cathepsin D shares 85%,91% amino acid (aa) sequences identity with human,rat Cathepsin D,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Cathepsin D recombinant protein (Position: E65-L410). Mouse Cathepsin D shares 85% and 91% amino acid (aa) sequences identity with human and rat Cathepsin D, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CTSD

Sujet:

Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

Gene Full Name: cathepsin D

Sequence Similarities: Belongs to the peptidase A1 family.

ID gène: 13033

UniProt: P18242

Pathways: Peptide Hormone Metabolism