CD82 anticorps (AA 98-267) (Cy3)

N° du produit ABIN7977462

Cet anticorps Lapin Polyclonal détecte spécifiquement CD82 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD82 anticorps (AA 98-267) (Cy3) (ABIN7977462)

Antigène: CD82

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD82 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-CD82 anticorps (Cy3)

Épitope: AA 98-267

Fonction: Anti-CD82 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CD82 shares 69%,67% amino acid (aa) sequences identity with mouse,rat CD82,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD82 recombinant protein (Position: A98-Y267). Human CD82 shares 69% and 67% amino acid (aa) sequences identity with mouse and rat CD82, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD82

Antigène: CD82

Autre désignation: CD82

Sujet:

Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

Gene Full Name: CD82 Molecule

Sequence Similarities: Belongs to the tetraspanin (TM4SF) family.

ID gène: 3732

UniProt: P27701

Pathways: Signalisation p53