CD82 anticorps (AA 32-266) (Fluoro550)

N° du produit ABIN7977475

L’anticorps anti-CD82 Polyclonal Lapin est utilisé pour la détection de CD82 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour CD82 anticorps (AA 32-266) (Fluoro550) (ABIN7977475)

Antigène: CD82

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD82 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-CD82 anticorps (Fluoro550)

Épitope: AA 32-266

Fonction: Anti-CD82 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse CD82 recombinant protein (Position: V32-Y266).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD82

Antigène: CD82

Autre désignation: Cd82

Sujet:

Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

Gene Full Name: CD82 antigen

ID gène: 12521

UniProt: P40237

Pathways: Signalisation p53