Ceruloplasmin anticorps (AA 20-259) (HRP)

N° du produit ABIN7978227

Cet anticorps Lapin Polyclonal détecte spécifiquement Ceruloplasmin dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ceruloplasmin anticorps (AA 20-259) (HRP) (ABIN7978227)

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ceruloplasmin est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Ceruloplasmin anticorps (HRP)

Épitope: AA 20-259

Fonction: Anti-Ceruloplasmin/CP Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8%,79.6% amino acid (aa) sequence identity with mouse,rat Ceruloplasmin,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8% and 79.6% amino acid (aa) sequence identity with mouse and rat Ceruloplasmin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Ceruloplasmin

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Autre désignation: CP

Sujet:

Background: Ceruloplasmin  (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Gene Full Name: ceruloplasmin

ID gène: 1356

UniProt: P00450

Pathways: Transition Metal Ion Homeostasis