Choline Acetyltransferase anticorps (AA 19-612)
Aperçu rapide pour Choline Acetyltransferase anticorps (AA 19-612) (ABIN7979618)
Antigène
Voir toutes Choline Acetyltransferase (CHAT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 19-612
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Fonction
- Anti-Choline Acetyltransferase/Chat Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Choline Acetyltransferase/Chat Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived rat Choline Acetyltransferase/Chat recombinant protein (Position: E19-D612).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Autre désignation
- Chat
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Sujet
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Background: Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Gene Full Name: choline O-acetyltransferase
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Poids moléculaire
- 71 kDa
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ID gène
- 290567
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UniProt
- P32738
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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