C19ORF80 anticorps (AA 22-198) (Fluoro550)

N° du produit ABIN7980062

Cet anticorps anti-C19ORF80 Polyclonal Lapin conjugué à Fluoro550 (ABIN7980062) détecte spécifiquement C19ORF80 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour C19ORF80 anticorps (AA 22-198) (Fluoro550) (ABIN7980062)

Antigène: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C19ORF80 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-C19ORF80 anticorps (Fluoro550)

Épitope: AA 22-198

Fonction: Anti-C19orf80/ANGPTL8 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human C19orf80 shares 74% amino acid (aa) sequence identity with mouse C19orf80.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human C19orf80 recombinant protein (Position: A22-A198). Human C19orf80 shares 74% amino acid (aa) sequence identity with mouse C19orf80.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur C19ORF80

Antigène: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Autre désignation: ANGPTL8

Sujet:

Background: ANGPTL8 (also known as lipasin, originally Betatrophin) is a protein that in humans is encoded by the C19orf80 gene. The gene for betatrophin lies on mouse chromosome 9 (gene symbol: Gm6484) and on human chromosome 19 (gene symbol: C19orf80). The encoded 22 kDa protein contains an N-terminal secretion signal and two coiled-coil domains and is a member of the angiopoietin-like (ANGPTL) protein family. However, in contrast to other ANGPTL proteins, betatrophin lacks the C-terminal fibrinogen-like domain, and therefore it is an atypical member of the ANGPTL family. It shares with Angptl4 and Angptl3 the ability to inhibit the enzyme Lipoprotein lipase (LPL), and its hepatic overexpression causes elevation of circulating Triglyceride levels in mice. In mice betatrophin is secreted by the liver. It was hoped that betatrophin or its homolog in humans may provide an effective treatment for type 2 diabetes and perhaps even type I diabetes.

Gene Full Name: angiopoietin like 8

ID gène: 55908

UniProt: Q6UXH0