CNTF anticorps (AA 2-198) (HRP)

N° du produit ABIN7980253

L’anticorps anti-CNTF Polyclonal Lapin est utilisé pour la détection de CNTF dans des échantillons de Rat et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour CNTF anticorps (AA 2-198) (HRP) (ABIN7980253)

Antigène: CNTF (Ciliary Neurotrophic Factor (CNTF))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CNTF anticorps (HRP)

Épitope: AA 2-198

Fonction: Anti-CNTF Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse CNTF shares 83%,95% amino acid (aa) sequences identity with human,rat CNTF,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse CNTF recombinant protein (Position: A2-M198). Mouse CNTF shares 83% and 95% amino acid (aa) sequences identity with human and rat CNTF, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNTF

Antigène: CNTF (Ciliary Neurotrophic Factor (CNTF))

Autre désignation: CNTF

Sujet:

Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The mouse CNTF gene is on mouse chromosome 19 and that its expression is unaffected in the mouse neurologic mutant wobbler, a form of spinal muscular atrophy. The CNTF protein is highly conserved in evolution. The protein is a potent survival factor for neurons and oligodendrocytes, and it may be involved in reducing tissue destruction during inflammatory attacks. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

Gene Full Name: ciliary neurotrophic factor

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

ID gène: 12803

UniProt: P51642

Pathways: Signalistation JAK/STAT