CNTF anticorps (AA 2-200) (Biotin)

N° du produit ABIN7980258

Cet anticorps Lapin Polyclonal détecte spécifiquement CNTF dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour CNTF anticorps (AA 2-200) (Biotin) (ABIN7980258)

Antigène: CNTF (Ciliary Neurotrophic Factor (CNTF))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CNTF anticorps (Biotin)

Épitope: AA 2-200

Fonction: Anti-CNTF Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84%,95% amino acid (aa) sequences identity with human,mouse CNTF,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84% and 95% amino acid (aa) sequences identity with human and mouse CNTF, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNTF

Antigène: CNTF (Ciliary Neurotrophic Factor (CNTF))

Autre désignation: CNTF

Sujet:

Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.

Gene Full Name: ciliary neurotrophic factor

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

ID gène: 25707

UniProt: P20294

Pathways: Signalistation JAK/STAT