Claudin 11 anticorps (C-Term) (PE)

N° du produit ABIN7980387

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 11 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Claudin 11 anticorps (C-Term) (PE) (ABIN7980387)

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Claudin 11 anticorps (PE)

Épitope: C-Term

Fonction: Anti-CLDN11 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human CLDN11, which shares 85% amino acid (aa) sequence identity with both mouse and rat CLDN11.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: CLDN11

Sujet:

Background: Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: claudin 11

ID gène: 5010

UniProt: O75508

Pathways: Hepatitis C