Claudin 7 anticorps (C-Term) (Fluoro550)

N° du produit ABIN7980514

L’anticorps anti-Claudin 7 Polyclonal Lapin est utilisé pour la détection de Claudin 7 dans des échantillons de Souris. Il a été validé pour FACS.

Aperçu rapide pour Claudin 7 anticorps (C-Term) (Fluoro550) (ABIN7980514)

Antigène: Claudin 7 (CLDN7)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Claudin 7 anticorps (Fluoro550)

Épitope: C-Term

Fonction: Anti-Claudin 7/CLDN-7 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 7/CLDN-7, which shares 87% and 100% amino acid (aa) sequence identity with human and rat Claudin 7/CLDN-7, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Cldn7

Sujet:

Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: claudin 7

ID gène: 53624

UniProt: Q9Z261

Pathways: Hepatitis C