Claudin 7 anticorps (C-Term)

N° du produit ABIN7980521

Cet anticorps anti-Claudin 7 Polyclonal Lapin (ABIN7980521) détecte spécifiquement Claudin 7 dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Claudin 7 anticorps (C-Term) (ABIN7980521)

Antigène: Claudin 7 (CLDN7)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-Claudin 7 anticorps

Épitope: C-Term

Fonction: Anti-Claudin 7/CLDN-7 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Claudin 7/CLDN-7 Antibody. Tested in WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 7/CLDN-7, which shares 87% and 100% amino acid (aa) sequence identity with human and rat Claudin 7/CLDN-7, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Cldn7

Sujet:

Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: claudin 7

Poids moléculaire: 22 kDa

ID gène: 53624

UniProt: Q9Z261

Pathways: Hepatitis C