Claudin 7 anticorps (AA 92-211) (HRP)

N° du produit ABIN7980528

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 7 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Claudin 7 anticorps (AA 92-211) (HRP) (ABIN7980528)

Antigène: Claudin 7 (CLDN7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Claudin 7 anticorps (HRP)

Épitope: AA 92-211

Fonction: Anti-Claudin 7/CLDN-7 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Claudin 7/CLDN-7 recombinant protein (Position: F92-V211).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: CLDN7

Sujet:

Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: claudin 7

ID gène: 1366

UniProt: O95471

Pathways: Hepatitis C