M-CSF/CSF1 anticorps (AA 33-262) (PE)

N° du produit ABIN7981258

L’anticorps anti-M-CSF/CSF1 Polyclonal Lapin est utilisé pour la détection de M-CSF/CSF1 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour M-CSF/CSF1 anticorps (AA 33-262) (PE) (ABIN7981258)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M-CSF/CSF1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-M-CSF/CSF1 anticorps (PE)

Épitope: AA 33-262

Fonction: Anti-MCSF/CSF1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 %,88.6% amino acid (aa) sequence identity with human,rat MCSF,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur M-CSF/CSF1

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: Csf1

Sujet:

Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Gene Full Name: colony stimulating factor 1 (macrophage)

Sequence Similarities: Contains 5 cadherin domains.

ID gène: 12977

UniProt: P07141

Pathways: Signalisation RTK